Differential Splicing

LeafletFA includes a differential_splicing module for testing whether splicing programs are differentially active between groups of cells, and for identifying junctions that drive those differences.

Testing differential SP activity

from leafletfa import differential_splicing

# Compare SP activities between two groups
results = differential_splicing.test_differential_activity(
    adata,
    groupby="cell_ontology_class",
    group1="T cell",
    group2="B cell",
)

API reference

See the full API: leafletfa.differential_splicing